NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 1 Discussion
DQ1 Part 1What are the differences between primary and secondary line of defense? What factors interfere with these mechanisms? How are these levels of immunity affected in a child, an elderly person, or a person with a chronic disease? Include active, passive, innate, and acquired immunity.
Part 2 Choose an inflammatory or infectious process and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.
DQ2 Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 2 Discussion
DQ1 The Beer's criteria contain a list of drugs that are potentially unsafe for use in older persons. Visit https://qioprogram.org/sites/default/files/2019BeersCriteria_JAGS.pdf. Select a drug on the "avoid" list that you have administered to an older patient or a drug that you know is prescribed for an older adult. Relate the outcome of using this drug to the pharmacokinetics (absorption, metabolism, distribution, and excretion) of drugs in an older client. In addition to the link, cite one other reference to support your post.
DQ2 Many people are using herbal medications and dietary supplements for the prevention and treatment of medical problems. Review two current research articles about two of these products. Based on the findings, what would be the implications for you as a nurse? What additional research needs to be done in this area? Cite the two references to support your answer.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 3 Discussion
DQ1 Choose a medical condition from the fluid, electrolyte, or acid-base system and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.
DQ2 Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 4 Discussion
DQ1 Choose a medical condition from the respiratory system or HEENT system and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.
DQ2 Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 5 Discussion
DQ1 Choose a medical condition from the cardiovascular system and lymphatic system and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.
DQ2 Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 6 Discussion
DQ1 Choose a medical condition from the gastrointestinal or genitourinary systems and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.
DQ2 Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 7 Discussion
DQ1 Choose a medical condition from the neurological, musculoskeletal, or integumentary system and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.
DQ2 Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 8 Discussion
DQ1 Choose a medical condition from the endocrine system and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.
DQ2 Select a medication used in evidence-based treatment guidelines for the condition chosen in the first discussion question. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions of which one should be aware. Make sure that you select a different medication than your peers. Include the name of the medication in the subject line so that the medications can be followed. Include your references in APA style.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 2 Assignment
Content Lesson Presentation
Create a 7-8 slide presentation with speaker notes about a selected disease process and drug class. The presentation should provide content specific information on the selected disease process and drug class for staff or students in a clinical environment.
Follow these steps:
Select a disease process and a drug class used to treat the disease process.
Describe pharmacokinetics and pharmacodynamics of the drug related to the pathophysiology of the disease process.
Describe the product, its intended use, side effects, adverse reactions, and safety issues.
Identify ethnic, cultural, and genetic differences in patients that may affect the safety or efficacy of medications.
How would you monitor the desired affect is achieved?
Be sure to include three to five references.
Refer to the resource, "Creating Effective PowerPoint Presentations," located in the Student Success Center, for additional guidance on completing this assignment in the appropriate style.
While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.
This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.
You are not required to submit this assignment to LopesWrite
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 3 Assignment
Acid-Base and Electrolyte Case Study
A nurse is taking care of an 85-year-old woman in a hospital-based skilled nursing facility. In the report, the nurse is told the patient has not been breathing well for the past 2 days. She has been lethargic, her skin is warm and dry, and she has a decreased urine output. The following laboratory findings were returned from the laboratory immediately after morning report:
Blood Chemistries
Na: 147
Cl: 110
K: 4.0
Blood Gases
pH: 7.33
PCO2: 48
HCO3: 27
PO2: 96
Urinalysis
Urine Specific Gravity: 1.040
Address the following:
Identify each of the abnormal laboratory findings in the above results. Specify how they differ from a normal range and identify what condition each abnormality indicates.
What specific electrolyte disturbance does the patient have?
What clinical manifestations would the nurse expect to see with this electrolyte abnormality presented above?
If the patient had an increase in her potassium level, what clinical manifestations would the nurse monitor for?
What blood gas abnormality is seen in this patient? Discuss the rationale for your answer.
What are the three major mechanisms of pH regulation?
While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.
This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.
You are not required to submit this assignment to LopesWrite.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 6 Assignment
CLC - Staff Training
This is a Collaborative Learning Community (CLC) assignment.
This assignment requires completion of two parts: a presentation and an educational resource.
Part I: Presentation
Create a 15- to 20-slide PowerPoint presentation with speaker notes for a staff training meeting on the pathophysiology and pharmacologic agents for a select disease process.
Each CLC will choose one disease process from the following list and obtain instructor approval to avoid duplication:
Alzheimer's disease
Asthma
Diabetes Type 2
Epilepsy
Gastroesophageal reflux disease (GERD)
Hypertension
Hypothyroidism
Multiple sclerosis
Peptic ulcer disease
Tuberculosis
Describe the physiology and pathophysiology of the disease, clinical manifestations, and evaluation (e.g., labs, imaging).
Describe the pharmacologic treatment of the disease, including pharmacokinetics, pharmacodynamics, drug interactions, side effects, adverse reactions, and application of the nursing process in monitoring the drug therapy.
Part II: Educational Resource
Using your selected disease process from Part I, develop an educational resource that can assist staff in increasing patient knowledge of medications and medication compliance.
The vehicle for your educational resource could include pamphlets, handouts, or any other brief, concise medium to convey the information to staff.
Refer to the resource, "Creating Effective PowerPoint Presentations," located in the Student Success Center, for additional guidance on completing this assignment in the appropriate style.
While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.
This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.
You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 5 Midterm Exam
• Low plasma albumin causes edema as a result of a reduction in which pressure?
Capillary hydrostatic
Interstitial hydrostatic
Plasma oncotic
Interstitial oncotic
• An increase of carbon dioxide in arterial blood causes chemoreceptors to stimulate the respiratory centers to:
decrease respiratory rate.
increase respiratory rate.
develophypocapnia.
develophypercapnia
• What is an example of compensatory hyperplasia?
Hepatic cells increase cell division after part of the liver is excised.
Skeletal muscle cells atrophy as a result of paralysis.
The heart muscle enlarges as a result of hypertension.
The size of the uterus increases during pregnancy.
• Bacteria that produce endotoxins that stimulate the release of inflammatory mediators that produce fever are called
pyrogenic bacteria.
true bacteria.
exotoxins.
spirochetes.
• Which NSAID is generally considered the safest for use in patients with coronary artery disease?
Celecoxib
Indomethacin
Naproxen
Acetaminophen
Cell wall inhibitors include all of the following except
penicillins.
cephalosporins.
carbapenems.
tetracylclines.
• In the immediate postnatal period, infants lose approximately 5% of body weight due to
loss of body water
inability of the body to digest nutrients
hemolysis of red blood cells
poor sucking reflex
•Heparin exerts its therapeutic action by:
upregulating the activity of one of the body's natural anticoagulant molecules, antithrombin III.
deactivating calcium-dependent clotting factors.
inducingprothrombin formation.
inducing the formation of fibrin.
• Pulmonary hypertension:
shows an enlarged pulmonary artery.
involves deep vein thrombosis.
shows right ventricular hypertrophy.
Shows an enlarged pulmonary artery and right ventricular hypertrophy.
• Which of the following factors do not influence bioavailability?
First-pass hepatic metabolism
Solubility of the drug
Bioequivalence
Chemical instability
NUR641E Advanced Pathophysiology and Pharmacology for Nurse Educators
Week 8 Final Exam
• What type of necrosis is associated with wet gangrene?
Coagulative
Liquefactive
Caseous
Coagulative
• Which agent is used to treat hepatic encephalopathy and works via "ion trapping,' converting ammonia into ammonium in the GI tract?
Rifaximin
Lactulose
Octreotide
Neomycin
• Cell wall inhibitors include all of the following except
penicillins.
cephalosporins.
carbapenems.
tetracylclines.
• Which of the following drugs acts on the parasympathetic nervous system?
Epinephrine
Atropine
Dopamine
Dobutamine
• Which of the following agents is preferred for the treatment of a patient who is asymptomatic with a serum sodium of 126?
3% NaCl
Tolvaptan
0.45% NaCl
0.9% NaCl
• One major reason to discontinue captopril (Capoten), an ACE inhibitor, is:
hypertension.
hypokalemia.
angioedema.
angina.
• Identify whether the description matches the disorder. (Select True or False)
Rotation of a testis, which twists blood vessels of the spermatic cord - Testicular torsion
True
False
• Which second-generation antipsychotic comes in an injectable formulation approved for use in acute psychosis?
Olanzapine
Quetiapine
Aripiprazole
Ziprasidone
• Which of the following drugs is most likely to reduce the effectiveness of levofloxacin (Levaquin) when given concomitantly?
Amiodarone (Cordarone)
Metronidazole (Flagyl)
Calcium carbonate (Tums)
Warfarin (Coumadin)
• The nurse has a patient who has been on multidrug therapy for pulmonary tuberculosis. When planning patient education, the nurse knows the patient needs to watch for which symptom of an adverse effect of multidrug therapy?
Hearing loss
Changes in vision
Generalized pruritus
Jaundice
• Which statement best describes cystic fibrosis?
Obstructive airway disease characterized by reversible airflow obstruction, bronchial hyperreactivity, and inflammation.
Respiratory disease characterized by severe hypoxemia, decreased pulmonary compliance, and diffuse densities on chest x-ray imaging.
Pulmonary disorder involving an abnormal expression of a protein-producing viscous mucus that obstructs the airways, pancreas, sweat ducts, and vas deferens.
Pulmonary disorder characterized by atelectasis and increased pulmonary resistance as a result of a surfactant deficiency.
• Stress-induced sympathetic stimulation of the adrenal medulla causes the secretion of:
epinephrine and aldosterone.
norepinephrine and cortisol.
epinephrine and norepinephrine.
acetylcholine and cortisol
• Identify whether the description of the skin lesion matches the disorder where it is found. (Select True or False)
Elevated, firm, and rough lesion with a flat top surface greater than 1 cm in diameter: Psoriasis or seborrheic and actinic keratoses
True
False
• What is the medical term for a fungal infection of the nail plate?
Paronychia
Onychomycosis
Tinea corporis
Tinea capitis
• Which hormone is required for water to be reabsorbed in the distal tubule and collecting duct?
Antidiuretic hormone
Aldosterone
Cortisol
Adrenocorticotropin hormone
• Identify whether the description of the skin lesion matches the disorder where it is found. (Select True or False)
Elevated, firm circumscribed area less than 1 cm in diameter: Wart (verruca) or lichen planus
•True
False
